Question

What role does the citric acid cycle play in amino acid metabolism?

a. breakdown of glucogenic amino acids feeds metabolites into the citric acid cycle

b. amino acid synthesis often relies on intermediates of the citric acid cycle

c. breakdown of ketogenic amino acids feeds metabolites into the citric acid cycle

a, b, & c

a & b

Answer 1

The correct answer is all A,B and C.

1.The glucogenic amino acids enter the Citric acid cycle only in intermediate form such as metabolites. These are converted into pyrvates by deamination and enter the TCA cycle as oxaloacetate or acetyl CoA intermediates.

2.TCA provides the intermediates that are used in amino acid synthesis. The oxaloacetate and alpha-ketoglutarate produce various types of amino acids.

3.Breakdown of ketogenic amino acids gives acetyl CoA which ia important intermediate for citric acid cycle.