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Polycystic kidney disease What is the etiology of the disease? 2. What's the the pathophysiology of...

Polycystic kidney disease

What is the etiology of the disease?

2. What's the the pathophysiology of the disease?

3. What's treatment of your disease?.

Typed please its hard for me to understand hand writing

Solutions

Expert Solution

Polycystic kidney disease is a genetic disease that causes many cysts to grow inside the kidneys.

  1. Etiology
  • Exact cause unknown
  • Genetic disorder
  • Gene abnormality
  • Gene mutation
  • Autosomal dominant
  • Family generation

2.pathophysiology

Polycystic kidney disease is a genetic disorder of renal cyst formation causing gradual enlargement of both kidneys in form of cyst , sometimes with progression to renal failure. Almost all forms are caused by a familial genetic mutation. Characterized by flank and abdominal pain, hematuria, and hypertension accumulation of fluid-filled cysts in the kidney and other organs. ADPKD is caused by mutations of either the PKD1 gene on chromosome 16 or the PKD2 gene on chromosome 4

3.Treatment

  • Treatments include medication to control blood pressure, pain relievers and cyst removal. A kidney transplant may also be required.
  • Medications

ACE inhibitor : lowers blood pressure and prevents diabetes-related kidney damage.

  • Low sodium diet
  • A diet that restricts salt
  • Hemodialysis-Using a machine and a special filter to clean the blood when the kidneys can no longer do it.
  • Peritoneal dialysis-A home-based therapy that uses the natural lining of the abdomen as a filter to clean the blood when the kidneys can no longer do so.
  • Renal replacement therapy-Using replacement treatments such as dialysis and haemofiltration to clean the blood when the kidneys can no longer do so naturally.
  • Kidney transplantation-Surgical replacement of a diseased kidney with one from a living or deceased donor.

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