Question

List all signs and symptoms of Myasthnia Gravis

Answer 1

Myasthenia gravis is an autoimmune disorder and a genetically inherited (from mother) disorder associated with imbalance muscular activity of both smooth muscle cells and skeletal muscles as predominantly due to blockade of acetylcholine receptors by host antibodies at the neuromuscular junction finally inhibiting excitatory postsynaptic (EPSPs) of acetylcholine neurotransmitter result in blockade of depolarization. This effect is leading blockade of action potentials produced by the motor neuron electrical signals leading to low depolarization rising phase by acting on the cholinergic ligand-gated nicotinic receptors of the motor end plate, where there receptor proteins are located inside the mosaic of lipid layer of phospholipids.

Myasthenia gravis signs and symptoms:

Trouble in talking

Double vision

Drooping of eyelids

Hoarse voice

Fatigue

Difficulty swallowing or chewing

Difficulty breathing because of muscle weakness

Facial paralysis

Problems walking up stairs or lifting objects