How eukaryotic cells communicate? Describe the mechanism of G-coupling protein receptors with diagrams.

Solutions

Expert Solution

Eukaryotic cells communicate through signalling.There are different type of signalling endocrine, paracrine , autocrine and juxtacrine.

These signalling occur when a ligand bind to the receptor and conformation changes occur in the receptor which further activate the other signal molecule and produce secondary messenger which activate the different protein kinase.

G protein coupled receptor is the cell surface receptors. When the ligand bind to the receptor conformation changes occur in receptor as a result GTP bind to the alpha subunit of G protein . After GTP binding alpha subunit get dissociate from the G protein trimeric subunit. Active alpha subunit bind to adenyl cyclase enzyme which is bound to the membrane and synthesized the cAMP from the ATP . cAMP bind to the regulatory subunit of protein kinase A . Protein kinase A get activated and dissociation of regulatory and catalytic subunit occur as a result catalytic subunit enter the nucleus and phosphorylate the target protein.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

Describe the features of G-protein coupled receptors in which show drugs or ligand that -act as...

Describe the features of G-protein coupled receptors in which show drugs or ligand that -act as an agonist and antagonist at those receptor types.

The three main types of cell surface receptors are ion-channel-coupled receptors, G-protein-coupled receptors, and enzyme-couple receptors....

The three main types of cell surface receptors are ion-channel-coupled receptors, G-protein-coupled receptors, and enzyme-couple receptors. They are all capable of binding extracellular signaling molecules but differ in how they relay that signal across the membrane. How does each type of surface receptor relay signal?

. Describe how the primary RNA transcript is modified in the nucleus of eukaryotic cells (unlike...

. Describe how the primary RNA transcript is modified in the nucleus of eukaryotic cells (unlike mRNA in prokaryotes) before exported to the cytoplasm for translation by ribosomes.

How do the BCR and TCR receptors and the MHC protein receptors interact for the lymphocyte...

How do the BCR and TCR receptors and the MHC protein receptors interact for the lymphocyte identification of the antigen?

What do both G protein-coupled receptors and tyrosine kinase receptors have in common? The binding site...

What do both G protein-coupled receptors and tyrosine kinase receptors have in common? The binding site for the signaling molecule is located on the outside of the cell. They both interact with G proteins. Binding of the signaling molecule forms a dimer. They both result in a phosphorylation cascade.

Describe mechanisms by which ion channels, protein phosphorylation and G-proteins give cells an ON or OFF...

Describe mechanisms by which ion channels, protein phosphorylation and G-proteins give cells an ON or OFF response for cell signaling. Describe this for each of these three processes, in the specific prompts below. Be sure be clear about where these mechanisms are distinct from one another. What are the inactive and inactive states? How does signal input activate the system? How is the system returned to inactive state?

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors)....

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors). Use ONE (1) specific example to explain each reception pathway. The details of the summary should be concise and informative. The length of the summary for each type of membrane receptor should be less than 200 words.

Compare and contrast signal transduction via tyrosine kinase receptors, G-protein receptors, and the IP3/DAG receptor pathways....

Compare and contrast signal transduction via tyrosine kinase receptors, G-protein receptors, and the IP3/DAG receptor pathways. Explain how it is possible for a primary messenger to illicit more than one response depending on the cell receiving the signal. In other words, how is it that increasing the concentration of one hormone can activate pathways in some tissues and activate or inhibit pathways in other tissues?

How does transcription in prokaryotic cells differ from transcription in eukaryotic cells?

How does transcription in prokaryotic cells differ from transcription in eukaryotic cells? List at least ten transcriptional processes (from primary transcript to mature RNA molecule) that eukaryotes need but prokaryotes do not

How does transcription in prokaryotic cells differ from transcription in eukaryotic cells?

Subjects