The three main types of cell surface receptors are
ion-channel-coupled receptors, G-protein-coupled receptors, and
enzyme-couple receptors....
The three main types of cell surface receptors are
ion-channel-coupled receptors, G-protein-coupled receptors, and
enzyme-couple receptors. They are all capable of binding
extracellular signaling molecules but differ in how they relay that
signal across the membrane. How does each type of surface receptor
relay signal?
54. Which of these receptor classes can activate G proteins
G protein coupled and ion channel receptors
Enzyme coupled receptors
G protein coupled receptors and enzyme coupled receptors
Ion channel coupled receptors
G protein coupled receptors
Explain the cell signaling pathway which involves membrane
receptor (tyrosine kinase receptors and G protein-coupled
receptors). Use ONE (1) specific example to
explain each reception
pathway.
The details of the summary should be concise and informative.
The length of the summary for each type of membrane receptor should
be less than 200 words.
QUESTION 1
Which of the following is an enzyme?
a G protein
a G protein-coupled receptor
ATP
All of the above
None of the above
1 points
QUESTION 2
Which of the following is true for all enzymes?
They alter the transition state.
They decrease ΔG.
They provide energy for endergonic reactions.
They harness energy from ATP.
1 points
QUESTION 3
The pathway of glycolysis can be found in:
Anaerobic bacteria only
Anaerobic species only
All bacteria, but...
40. unlike membrane G protein couple receptors some
ligand gated ion channels can be directly activated by cytosolic
second messengers.
a. true
b. false
2. Arrestin-mediated internalization of GPCRs
terminates the GPCR signaling. The binds of arrestin is facilitated
by ____ .
a. Inactivation of GPCR
b. GPCR in endosome
c. G-protein-couple receptor kinase (GRK)-mediated
phosphorylation
d. dephosphorylation of GPCR
12. Checkpoints halt the progress of the cell cycle
when:
a. The DNA cannot be repaired in cancer cells
b....
What do both G protein-coupled receptors and tyrosine kinase
receptors have in common?
The binding site for the signaling molecule is located on the
outside of the cell.
They both interact with G proteins.
Binding of the signaling molecule forms a dimer.
They both result in a phosphorylation cascade.
Upon binding of a ligand, G-protein-coupled receptors do which
of the following?
Select one:
a. The G-protein exchanges a GDP for a GTP, and the alpha
subunit detaches from the beta/gamma complex
b. They dimerize, autophosphorylate, and trigger a cascade in
intracellular signal transduction/phosphorylation
c. They migrate to the nucleus to activate/repress specific
genes
d. They get internalized and start producing cAMP
e. They induce apoptosis
structure and function of G-protein coupled receptors: binding of
neurotransmitter/ hormone to 7-transmembrane receptor, activation
of G protein (3 subunits- what happens with each subunit), role of
GTP/GDP (AH domain)