Describe the features of G-protein coupled receptors in which show drugs or ligand that -act as...

Describe the features of G-protein coupled receptors in which show drugs or ligand that -act as an agonist and antagonist at those receptor types.

Solutions

Expert Solution

ANS)

The G protein-coupled receptors,contain a big protein family of receptors which identify molecules that are present outer part of the cell and trigger the internal transduction pathways and eventually the cellular responses coupling with the G-proteins and the G protein -coupled receptors are also having an another name and that is,Seven-transmembrane receptors.This name has given to them because they travel by the means of cell membrane for 7 times.

The G-Protein-coupled receptors is having an important task in assisting cell communication by identification of various ligans,involving the nucleosides, lipids,amines and also the bioactive peptides.

These G protein- coupled receptors are normally seen only in the eukaryotes,involving choanoflagellates,yeast and also the animals.

Drugs or ligands that act as an agonist and antagonist at the G protein-coupled receptors include,neurotransmitters, hormones, light- sensitive compound, pheromones and ordors.

THANKS!!!

Sydney Mullin answered 11 months ago

Next > < Previous

Related Solutions

Upon binding of a ligand, G-protein-coupled receptors do which of the following? Select one: a. The...

Upon binding of a ligand, G-protein-coupled receptors do which of the following? Select one: a. The G-protein exchanges a GDP for a GTP, and the alpha subunit detaches from the beta/gamma complex b. They dimerize, autophosphorylate, and trigger a cascade in intracellular signal transduction/phosphorylation c. They migrate to the nucleus to activate/repress specific genes d. They get internalized and start producing cAMP e. They induce apoptosis

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors)....

Explain the cell signaling pathway which involves membrane receptor (tyrosine kinase receptors and G protein-coupled receptors). Use ONE (1) specific example to explain each reception pathway. The details of the summary should be concise and informative. The length of the summary for each type of membrane receptor should be less than 200 words.

What do both G protein-coupled receptors and tyrosine kinase receptors have in common? The binding site...

What do both G protein-coupled receptors and tyrosine kinase receptors have in common? The binding site for the signaling molecule is located on the outside of the cell. They both interact with G proteins. Binding of the signaling molecule forms a dimer. They both result in a phosphorylation cascade.

QUESTION 1 Which of the following is an enzyme? a G protein a G protein-coupled receptor...

QUESTION 1 Which of the following is an enzyme? a G protein a G protein-coupled receptor ATP All of the above None of the above 1 points QUESTION 2 Which of the following is true for all enzymes? They alter the transition state. They decrease ΔG. They provide energy for endergonic reactions. They harness energy from ATP. 1 points QUESTION 3 The pathway of glycolysis can be found in: Anaerobic bacteria only Anaerobic species only All bacteria, but...

structure and function of G-protein coupled receptors: binding of neurotransmitter/ hormone to 7-transmembrane receptor, activation of...

structure and function of G-protein coupled receptors: binding of neurotransmitter/ hormone to 7-transmembrane receptor, activation of G protein (3 subunits- what happens with each subunit), role of GTP/GDP (AH domain)

Explain what specific signaling information processing happens in the case of GPCR (G protein Coupled Receptors).

Multiple Can Be Correct. All of the following are correct about G protein-coupled receptors(GPCR) EXCEPT: After...

Multiple Can Be Correct. All of the following are correct about G protein-coupled receptors(GPCR) EXCEPT: After agonist-induced activation, GPCRs are NOT desensitized. GPCRs contain 7 hydrophobic regions thought to represent their transmembrane domains. You can sometimes demonstrate that a receptor is coupled to a G protein by using pertussis toxin or cholera toxin. The target proteins for approximately 40-50% of the drugs on the market are GPCRs. GPCRs contain multiple serine, threonine and tyrosine residues which can be phosphorylated.

40. unlike membrane G protein couple receptors some ligand gated ion channels can be directly activated...

40. unlike membrane G protein couple receptors some ligand gated ion channels can be directly activated by cytosolic second messengers. a. true b. false 2. Arrestin-mediated internalization of GPCRs terminates the GPCR signaling. The binds of arrestin is facilitated by ____ . a. Inactivation of GPCR b. GPCR in endosome c. G-protein-couple receptor kinase (GRK)-mediated phosphorylation d. dephosphorylation of GPCR 12. Checkpoints halt the progress of the cell cycle when: a. The DNA cannot be repaired in cancer cells b....

HUMAN GROWTH HORMONE 1. Describe the ligand and any external receptors that bind to the ligand....

HUMAN GROWTH HORMONE 1. Describe the ligand and any external receptors that bind to the ligand. If signaling can occur without an external ligand, explain how this can occur. 2. Describe how the signal is translocated from the exterior of the cell to the interior of the cell. Be sure to describe the specific activity of the receptor in initiating the intracellular signal. 3. Describe the propagation of the signal within the cell from the membrane receptor to the point...

54. Which of these receptor classes can activate G proteins G protein coupled and ion channel...

54. Which of these receptor classes can activate G proteins G protein coupled and ion channel receptors Enzyme coupled receptors G protein coupled receptors and enzyme coupled receptors Ion channel coupled receptors G protein coupled receptors

Subjects