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For the question, please explain and provide details During B-cell activation some activated B-cells undergo differentiation...

For the question, please explain and provide details

During B-cell activation some activated B-cells undergo differentiation into antibody secreting plasma cells outside of the germinal center and therefore never go through the germinal center responses. Other activated B-cells will return to the follicle forming a germinal center and undergo processes that alter the antibody that will be produced.

Describe the germinal center responses. Why are these responses important (hint: what is different about the antibody produced)? Why are T cells important in germinal center responses?

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