Question

In: Chemistry

There are three buffer systems that control the pH of body fluids. One of the buffer...

There are three buffer systems that control the pH of body fluids. One of the buffer systems depeneds on proteins acting as either proton acceptors or proton donors at different pH values. What are the other two biological systems? Explain the way they work.

Solutions

Expert Solution

Other two buffer systems of our body are carbonic acid - bicarbonate buffer system and phosphate buffer system.

H2CO3 - HCO3- : CARBONIC ACID - BICARBONATE BUFFER
Cellular respiration produces CO2 as a waste product. This is immediately converted to bicarbonate ion in the blood.

CO2 + OH- <==> HCO3-

On reaching the lungs it is again converted to and released as carbon dioxide. While in the blood , it neutralises acids released due to other metabolic processes.

HCO3- + H+ <==> CO2 + H2O

In the stomach and deudenum it also neutralises gastric acids and stabilises the intra cellular pH of epithelial cells by the secretions of bicarbonate ions into the gastric mucosa.

H+ + OH- <==> H2O

PHOSPHATE BUFFER SYSTEM
Phosphate buffer system operates in the internal fluids of all cells. It consists of dihydrogen phosphate ions as the hydrogen ion donor ( acid ) and hydrogen phosphate ion as the ion acceptor ( base ) .

If additional hydroxide ions enter the cellular fluid, they are neutralised by the dihydrogen phosphate ion.

H2PO4- + OH- <==> HPO42- + H2O

If extra hydrogen ions enter the cellular fluid then they are neutralised by the hydrogen phosphate ion.

HPO42- + H+ <==> H2PO4-

The main purpose of all these buffers is to maintain proper pH within the body system so that all biochemical process can take place.

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