A mother has two children. The first was born perfectly healthy while the second one was...

A mother has two children. The first was born perfectly healthy while the second one was born with rashes, showed clumping and lysis of blood. Based upon this information how would you classify this disorder? What type of antibody-antigen interaction is this and why? Explain how this disorder arises.

Expert Solution

This type of disorder is usually called Hemolytic anemia of newborn or Erythroblastosis fetalis. In this disorder, antibodies are developed against Rh antigen present on the surface of RBCs of the fetus.

During the first pregnancy, the Rh-negative mother carrying Rh-negative fetus in the womb doesn't produce antibodies. But the

Rh-negative mother carrying Rh-positive fetus in the womb produces antibodies against the RBCs of the fetus.

Therefore due to the significant separation between mother and fetus by the placenta antibodies do not pass to the fetus during the first pregnancy.

But during the second pregnancy, the placenta is not able to well separate the Rh-ve mother carrying the Rh-positive fetus, therefore during delivery, the antibodies pass to the baby through the placenta and bind to the Rh antigen on RBCs. The binding of the antibody to the Rh Antigen leads to the clumping reaction and its lysis thereby causing hemolytic anemia.

The name itself suggests Heme= red part of RBCs, Lytic = lysis

so prevent the baby from this disorder, RhoGAM injection is given which are the antibodies against Anti-Rh

gladiator answered 2 years ago

7. A mother has two children. The first was born perfectly healthy while the second one...

7. A mother has two children. The first was born perfectly healthy while the second one was born with rashes, showed clumping and lysis of blood. Based upon this information how would you classify this disorder? What type of antibody-antigen interaction is this and why? Explain how this disorder arises

Case Study B: Ms. J. is a 30-year-old healthy single mother with two children. She has...

Case Study B: Ms. J. is a 30-year-old healthy single mother with two children. She has worked as a paramedic in her community for 6 years. She and her partner responded to a call involving a man who had been drinking heavily at a family party and who was partially conscious. When she and her partner attempted to transfer the 100-kg man to a stretcher, the man grabbed her neck, causing her severe pain. Ms. J.’s doctor diagnosed a spinal...

In 2017, the first baby was born in the U.S. to a mother who had received...

In 2017, the first baby was born in the U.S. to a mother who had received a uterus transplant, meaning a uterus donated by another human female was implanted into the mother and this a transplanted uterus was the site of implantation, and development of the fetus to term. Obviously, this type of medical procedure is not without challenges and risks. Briefly describe three possible challenges of uterus transplantation (anywhere from initial surgery to childbirth) - one challenge must relate...

If a mother had blood type _____, her second baby and subsequent children would be endangered...

If a mother had blood type _____, her second baby and subsequent children would be endangered if they had type A+. a. type A– blood b. type A+ blood c. type B+ blood d. type O+ blood Which of the following statements about human blood is false? a. blood plasma makes up more than half of the volume of normal blood b. blood plasma is mostly water, with ions, amino acids, glucose, hormones, proteins, and other materials c. white blood...

First-born children tend to develop language skills faster than their younger siblings. One possible explanation is...

First-born children tend to develop language skills faster than their younger siblings. One possible explanation is that they have undivided attention from their parents. If this is correct, then triplets should be slower. The following hypothetical data demonstrate potential measure of language skill from such a study. Do the data indicate significant differences? Show all work. Single Child: 8, 7, 10, 6, 9 Triplet: 4, 4, 7, 2, 3

Congratulations! Your first baby was born yesterday and is healthy and strong. To guard against your...

Congratulations! Your first baby was born yesterday and is healthy and strong. To guard against your premature death, you want to purchase a life insurance policy that will replace $58,000 of your annual income until your child is 20 years old. How much life insurance should you purchase, if you assume a 3% inflation rate? and please note what formula you used: 1. future value 2. present value annuity 3. future value payment or 4.present value

Calculate ANOVAs for the following two problems. Show all your work. First-born children tend to develop...

Calculate ANOVAs for the following two problems. Show all your work. First-born children tend to develop language skills faster than their younger siblings. One possible explanation is that they have undivided attention from their parents. If this is correct, then twins should show slower language development than single children, and triplets should be even slower. The following hypothetical data demonstrate potential measure of language skill from such a study. Do the data indicate significant differences? Single Child: 8, 7, 10,...

Katie is a 7-month-old baby girl, the second child born to her parents. Her mother had...

Katie is a 7-month-old baby girl, the second child born to her parents. Her mother had a healthy, full-term pregnancy, and Nona’s birth weight was normal. She did not respond well to breastfeeding and was changed entirely to a formula based on cow’s milk at 4 weeks. Between 7 and 12 weeks of age, she was admitted to the hospital twice with a history of screaming after feeding, but was discharged after observation without a specific diagnosis. Elimination of cow’s...

Oscar Franklin Jr., a 9-day-old male, was born full-term, thought to be healthy, and discharged second...

Oscar Franklin Jr., a 9-day-old male, was born full-term, thought to be healthy, and discharged second day postpartum. His sister, Elizabeth, 5 years old, just came down with rubella. Oscar is brought in today by his mother to see Dr. Belkin, his pediatrician. After a thorough examination, Oscar is diagnosed with congenital rubella pneumonitis.

You are given two containers, the first containing one litre of wine and the second one...

You are given two containers, the first containing one litre of wine and the second one litre of water. You also have a cup which has a capacity of r litres, where 0 < r < 1. You fill the cup from the first container and transfer the content to the second container, stirring thoroughly afterwards. Next, dip the cup in the second container and transfer r litres of liquid back to the first container. This operation is repeated again...

Question