Question

In: Biology

Discuss whether glucagon and epinephrine act in the same way in liver, muscle and heart cells...

Discuss whether glucagon and epinephrine act in the same way in liver, muscle and heart cells in terms of their effects on glycolysis and gluconeogenesis

Solutions

Expert Solution

Glucagon responds when glucose is too low, and the tissues respond by producing glucose through glycogen breakdown and gluconeogenesis and by oxidizing fats to reduce the use of glucose.Epinephrine  is released into the blood to prepare the muscles, lungs, and heart for a burst of activity.Glucagon has potent positive inotropic and chronotropic effects on the heart. This endogenous hormone plays no significant role in the normal regulation of the cardiovascular system, but it has been used to treat various cardiac conditions. Glucagon and epinephrine trigger the breakdown of glycogen. Muscular activity or its anticipation leads to the release of epinephrine ,a catecholamine from the adrenal medulla. Epinephrine stimulates glycogen breakdown in muscle and in the liver. The liver is responsive to glucagon,  a polypeptide hormone that is secreted by the α cells of the pancreas when the blood-sugar level is low. Glucagon also signifies the starved state.


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