In: Biology
Heart muscle contains a form of PFK-2/FBPase-2 that is different from that in liver. In heart muscle, phosphorylation of PFK-2/FBPase-2 by protein kinase A (also called cAMP-dependent protein kinase) activates PFK-2 and inhibits FBPase-2. Explain why this makes metabolic sense for a response of heart muscle to epinephrine. (Heart muscle cells have receptors for epinephrine, but not for glucagon.)