In: Chemistry
In muscle tissue, the ratio of phosphorylase a to phosphorylase b determines the rate of conversion of glycogen to glucose 1‑phosphate.
Classify how each event affects the rate of glycogen breakdown in isolated muscle tissue.
Increased rate
Decreased rate
No change
Answer Bank
AMP allosteric binding activates phosphorylase b
removal of phosphate groups from phosphorylase a
addition of phosphorylase b kinase
[ATP] exceeds [AMP]
addition of a kinase inhibitor
treatment with insulin
addition of a phosphatase inhibitor
treatment with glucagon