What symptoms are associated with major depression? How are glucocorticoid levels changed for many people with...

What symptoms are associated with major depression?
How are glucocorticoid levels changed for many people with depression?
How are glucocorticoid changes related to memory in people with depression?
Do glucocorticoid levels change the same for people with atypical depression?
Describe how different affective styles impact our responses to stress.
Describe the variables that the male baboons possess, that cope the best with stress (have lower glucocorticoid levels).
Describe the difference between fear and anxiety.
Is anxiety dominated by catecholamines or glucocorticoids?
How are hostility and cardiovascular disease related?

dont need to be long just two or 3 sentences at most for a-i please

Expert Solution

Answer

1. Some of the core symptoms which are associated with the major depression or the major depressive disorder are

Sleep Disturbance
Fatigue
Change in apetite
Loss/gain in weight
Recurrent suicidal thoughts
Loss of inetrest/pleasure
Depressed mood

2. People who suffer from depression show chnages in the glucocorticoid levels because of a disordered HPA axis glucocorticoid feedback mechanism. An increased levels of the glucocorticoid hormone cortisol is seen in almost 50% of patients who suffer from depression. The GR function is imapired in depression which causes changes in the levels of glucocorticoid.

3. In a depressed brain, the imapired GR funtions and the abnormalities in the cortisol levels result in various changes such as memory acquisition or neuronal survival etc. The memory acquisition is regulated by cortisol, and a no. of abnormalities are noticed in cortisol levels in a depressed brain.

4. The answer to whether glucocorticoid level show similar changes in aytpical depression would be no. People who suffer from atypical depression do not exhibit elevated levels basal corticol instead, show increased HPA sensitivity to glucocorticoid feedback and also exhibit HPA hypoactivity.

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Hayet Jeridi answered 1 year ago

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