Question

What is a glucocorticoid hormone and how does it influence the body? How could this influence be a good thing in the short term, but cause problems in the long term?

Answer 1

• GLUCOCORTICOID HORMONE are corticosteroid hormone,steroid in nature released from adrenal gland also called adrenal steroid cortisol

when in anterior lobe of pituarty gland,adrenocorticotropic hormone, released which cause release of glucocorticoid from th adrenal gland

. Glucocorticoids are necessary for the body’s normal response to stress, and they also have anti-inflammatory effects

major function of glucocorticoid is

A.immunological

B.MEtabolic

EFFECT OF GLUCOCORTICOID

1.ON BRAIN -

• A. APETITE STIMULATION
• B.PREFERENCE FOR CALORIE DENSE FOOD

2.ON CENTRAL FAT

• A. INCREASE ADIPOGENESIS
• B. INCREASE DIFFERENTIATION
• C INCREASE HYPERTROPHY

.3. ON PERIPHEREAL FAT

• A.INCREASE LIPOLYSIS
• B DECREASE LPL ACTIVITY

4 IN BROWN ADIPOSE TISSUE

• A DECREASE THERMOGENESISCAUSE ADIPOSE EXTENSION AND REDISTRIBUTION

ON INFLAMMATORY CELL

• . DECREASE CYTOKINE IN MACROPHAGE
• DECREASE EOSINOPHIL
• DECREASE MAST CELL
• DECREASE DENDRITIC CELL

ON STRUCTURAL CELL

• DECREASE MUCUS SECRETION FROM MUCUS GLAND
• DECREASE CYTOKINE MEDIATOR FROM EPITHELIAL CELL
• DECREASE BETA RECETOR FROM SMOOTH CELL
• DECREASE LEAKAGE FROM ENDOTHELIAL CELL