Question

In: Biology

Which of the following cell types express telomerase to maintain their telomere lengths and extend their...

Which of the following cell types express telomerase to maintain their telomere lengths and extend their replication abilities?

Select one:

- somatic cells

- neurons

- liver cells

- stem cells

Solutions

Expert Solution

Ans.

  • Telomerase is an enzymes found in somes cells which help to extend the telomeres of their chromosomes.
  • This enzyme belongs to the class of RNA-dependent DNA polymerase because of it's ability to synthesize DNA by using RNA as a template.
  • Telomerase remains inactive in most of the somatic cells but is found active in germ cells and many adult stem cells.
  • Telomerase helps increase the length of telomeres, which are repetitive stretches of DNA at the chromosomes tips.
  • Over time, telomeres shorten in length, thus increasing the risk to damage chromosomes which may lead to cell death.
  • One exception of such type of cells dying is stem cells.
  • Stem cells uses telomerase to build their telomeres again and again, thus providing the ability of dividing and developing to them.
  • This phenomenon increses the replication ability of stem cells and they can develop into any type of cell for the specific tissue or organ such as skin or liver.
  • This unique feature of stem cell is known as pluripotency.
  • Pluripotency of stem cells is being explored for regenerative therapies for the treatment of age related cellular diseases and damages.

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