Will combining Thr and Phe into the dipeptide Thr-Phe will release a molecule of water? Please...

Will combining Thr and Phe into the dipeptide Thr-Phe will release a molecule of water?

Please show work, thank you!

Expert Solution

Hi,

Phenylalanyl-Threonine is a dipeptide composed of phenylalanine and threonine. It is an incomplete breakdown product of protein digestion or protein catabolism. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following further proteolysis. This dipeptide has not yet been identified in human tissues or biofluids and so it is classified as an 'Expected' metabolite.

Yes combining Phenylalanine and threonine will result in formation of dipeptide and release of water molecule as shown in below structures

Structure of dipeptide (Phenylalanyl-Threonine; Molecular weight: 266)

Structure of Threonine; Molecular weight: 119

Structure of Phenylalanine , Molecular weight: 165

Looking at the individual structures of threonine and phenylaline, it is clear that, Threonine looses the -H group while phenylalanine looses -OH group to release water to form thr-phe dipeptide

queen_honey_blossom answered 1 year ago

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