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Environmental fate of medications Medications can enter wastewater management systems either through human excretions or through improper disposal.

Environmental fate of medications Medications can enter wastewater management systems either through human excretions or through improper disposal. Many medications are not effectively treated by current wastewater management processes and therefore are discharged by wastewater treatment plants. Antidepressants are some of the most commonly prescribed medications in the United States, and many antidepressants are not effectively managed by wastewater treatment plants. a. A wastewater treatment plant discharges to Boulder Creek in Colorado at a rate of 64 million L/day, and the stream flow, upstream of the wastewater discharge point, is 1110 L/s. If the concentration of the antidepressant venlafaxine (Effexor) measured in the creek water is 10 ng/L, what is the mass discharged per day from the wastewater treatment plant, assuming that there are no sources other than the wastewater treatment plant, and assuming that the drug rapidly equilibrates among sediment, fish, and water? What is the concentration of the medication in the wastewater treatment plant effluent? BCF = 40.27 KOC = 3.162 Organic sediment = 15 ppm Biota concentration = 5 g/100 m3 b. A man fishing near the outflow point of Boulder Creek eats 0.2 kg of fish from the creek. How much venlafaxine will he ingest? One dose of Effexor contains 75 mg of venlafaxine. What percentage of a dose will the fisherman ingest?

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Expert Solution

• Wastewater scheme organization has plated for efficient removal of solid and dissolved wastes and make it drainage clever to some stream corpse without some kind of contagion to be extend.

• As the situation now is that Americans are by extra figure of set Antidepressants and finally the squander or a lot of it is receiving washed to the big drainage scheme.

• As missing the good excellence verify and scheme to take away such checkup substances from stream basis they are opposite large confront. Here the medicine named Paroxetine HCl (Paxil) is mainly in center.

• The squander stream organization is organization to resolve the wastes stream into a flow at a speed of 64 million L/day. The wastewater discharge point, the stream flow is 1,110 L/s.

• Antidepressant paroxetine HCl (Paxil) calculated in the lake is 10 ng/L. So for per next flow speed with the free gets 1110 * 10 nanogram (ng)/ second = 11.1 microgram = 0.0111 milligram (mg)/ second.

• This makes the attentiveness for the creek free speed of 64 million L/day. So, calculating for 1 million liter 100,000 liter = 1million liter, for 64 million liters = 64000,000 / day.

• For 24 hours it becomes 24 60 (1 hour) 60 (per second) = 86400 seconds per day. Water flows at 1110 liter/ second, so for a entire day the flow will be = 95904000 liters,

• Calculating the drug is getting ousted is = 95904000 * 0.0111 mg of drug/second = 1064534 mg for 24 hours in that stream = 1.064534 grams/day.

• This is the calculation for accumulation free per day. attentiveness per effluent is = 0.0111 milligram (mg)/ second. .


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