Question

In: Biology

Describe the similarities and differences of aminocyclitol, iminosugar, aminosugar, aminoglycoside, and glycosylamine. Shown one example for...

Describe the similarities and differences of aminocyclitol, iminosugar, aminosugar, aminoglycoside, and glycosylamine. Shown one example for each.

Solutions

Expert Solution

Differentiating criteria

Amino Sugar

Imino Sugar

Aminoglycoside

Glycosamine

Aminocyclitol

Structure

In this case, the Hyroxyl group of sugar molecule is replaced by Amino/Acetylamino group

In this case, an oxygen atom of a sugar molecule is replaced by Nitrogen atom

The amino glycoside are formed by a complex of Aminosugar and a dibasic aminocyclitol. The later is connected by glycosidic linkage.

It is formed of Amino group attached to Glycosyl group and thus they are called as N-glycosides

They consist of carbon rings having Amine group(NH2) as the main functional groups.They The carbon rings are called Cycloalkanes , with at least 3 Hydroxyl groups(OH).

Uses/importance

N-acetylglucosamine forms a component of the bacterial cell wall.

Some of the Iminosugars are used as Antiviral molecules

They are mostly used as antibiotics

Now a days they are being used as glycoside mimics

They have clinical application( as antibiotics) as well as agricultural application.

example

N-acetylglucosamine , which is a glucosamine derivative is a amino sugar

1-deoxynojirimycin

Kanamycin A

Adenosine

Hygromycon B

Similarity among all-- They are all Sugar derivatives


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