Cell Biology Short Answer Question: Review the
steps for ligand-induced activation of effector protein mediated by
trimeric G proteins. Suppose you have isolated a mutant Gα that has
increased GTPase activity, what effect would this mutation have on
the G protein and the effector protein?
Describe the classical pathway of complement activation in the
absence of antibodies and how it is used during an innate immune
response to clear the pathogen.
List and explain the 3 mechanisms that are related with
activation of a protooncogene into an oncogene.
b. Discuss the importance of oncogenes in tumorigenesis.
Which of the following statements does not describe the
classical activation pathway of complement?
A) Initiation of the classical pathway of the complement system
requires formation of an antibody antigen complex.
B) The classical pathway results in complement activation of the
inflammatory response only.
C) The classical pathway converges with the alternative pathway,
resulting in the same possible complement-mediated immune
responses.
D) The classical pathway is an example of an adaptive immune
response.
one effect of antibodies produced during humoral immunity is to
trigger activation of the complement system. Despite this, the
complement system is considered part of the innate immune system.
explain why
Describe the activation of the complement system making sure to
list the three major outcomes. Give two examples of mechanisms by
which a parasite we discussed in lecture evades complement
activation.
1. compare and contrast the classic and alternative
pathway of complement activation. which pathway is most directly
tied in with the immune response?
2. How is a person's susceptibility to infection altered by
complement deficiencies?