Question

1. A person living at high altitude, where the partial pressure of oxygen is very low, would likely have high levels of __________ in their plasma which __________ the affinity of hemoglobin for oxygen.
   1. 2,3-DPG; increases                                          b. myoglobin; decreases

                       c.    myoglobin; increases                                                         d. 2,3 DPG; decrease

1. Increased calcium entry into vascular circular smooth muscle cells could be caused by increased ________ near the afferent arterioles supplying the glomerulus thus ________ the glomerular filtration rate.
   1. ADH; decreasing
   2. ANG II; increasing
   3. ANP; decreasing
   4. Aldosterone; increasing

Answer 1

1) A person living at high altitude, where the partial pressure of oxygen is very low, would likely have high levels of __2,3-DPG________ in their plasma which ___decrease_______ the affinity of hemoglobin for oxygen.

Answer: d) 2,3 DPG; decrease

Explanation:- At high altitude, the count of the red cell is high, the affinity of the Hb fro oxygen decreases in order to release more oxygen to the tissue. Hence the level of 2,3-DPG is high which causes shifting of O2 dissociation curve towards right leading to less affinity to O2.

2. Increased calcium entry into vascular circular smooth muscle cells could be caused by increased __ADH______ near the afferent arterioles supplying the glomerulus thus ___decreasing_____ the glomerular filtration rate.

Answer: a. ADH; decreasing

Explanation: Constriction of the afferent arterioles increases the vascular resistance which reduces renal blood flow (RBF), and it decreases the pressure downstream from the constriction that reduces the GFR.