Which of the following will decrease the affinity of oxygen for hemoglobin at low oxygen partial...

Which of the following will decrease the affinity of oxygen for hemoglobin at low oxygen partial pressures and shift the oxyhemoglobin saturation curve to the right, resulting in increased oxygen unloading for active tissues?

Select one:

a. high CO₂

b. low H⁺

c. low temperature

d. high hemoglobin levels

e. low CO₂

Solutions

Expert Solution

A. High CO2 is the correct answer.

High CO2 will shift the curve to the right and cause O2 unloading at the level of tissue.

An eg. is given below

Unsat. & Sat. means unsaturated and saturated.

Red. Means reduced.

Hb is hemoglobin

P 50= partial pressure.

Sydney Mullin answered 1 year ago

Next > < Previous

Related Solutions

Explain, how following conditions influence affinity of hemoglobin and myoglobin to oxygen: a) falling of pH...

Explain, how following conditions influence affinity of hemoglobin and myoglobin to oxygen: a) falling of pH in blood plasma from pH=7.4 to pH=7.2. b) falling of partial pressure of CO2 from 6 kPa to 2 kPa c) Increase in BPG level from 5 mM to 8 mM.

Describe the relationship between the partial pressure of oxygen and the binding of oxygen to hemoglobin.

Why does hemoglobin have a lower affinity for the first oxygen molecule it binds than it...

Why does hemoglobin have a lower affinity for the first oxygen molecule it binds than it does for the binding additional molecules?

What is the effect of the following changes in the O2 affinity of hemoglobin? (a) A...

What is the effect of the following changes in the O2 affinity of hemoglobin? (a) A drop in the pH of blood plasma from 7.4 to 7.2. (b) A decrease in the partial pressure of CO2 in the lungs from 6 kPa (holding one’s breath) to 2 kPa (normal). (c) An increase in the BPG level from 5 mM (normal altitudes) to 8 mM (high altitudes). (d) An increase in CO from 1.0 part per million (ppm) in a normal...

1. Explain how the oxygen affinity of hemoglobin can affect the followings: 1.1 Amino acid substitutions...

1. Explain how the oxygen affinity of hemoglobin can affect the followings: 1.1 Amino acid substitutions that disrupt H-bonding at the α,β-interface 1.2 Substitution L136P, which destabilizes the subunit interactions 1.3 Disease in which the individual has increased levels of fetal hemoglobin 1.4 Consumption of methanol that causes a drop in blood pH (Metabolic acidosis)

Synthesis of a Cobalt Complex that Mimics Oxygen Binding in Hemoglobin Knowing the decrease in volume...

Synthesis of a Cobalt Complex that Mimics Oxygen Binding in Hemoglobin Knowing the decrease in volume at ambient temperature and atmospheric pressure, the number of moles of O2 absorbed per mole of Co(salen) can be calculated. From your oxygen uptake experiments, how many equivalents of oxygen are bound to the cobalt? Draw the structure of your proposed molecule (you will need to know the amount of Co(salen) you added to the sidearm flask and the change of volume you observed...

According to the Oxygen-Hemoglobin Saturation Curve (= Oxygen-Hemoglobin Dissociation Curve):

1.Which of the following statements is NOT an explanation for how oxygen is released from oxy-hemoglobin....

1.Which of the following statements is NOT an explanation for how oxygen is released from oxy-hemoglobin. A. Carbon dioxide has a stronger affinity than oxygen to heme and displaces oxygen in tissues. B. The formation of carbonic acid lowers the oxygen affinity of hemoglobin in tissues. C. The structure of deoxyhemoglobin is stabilized by the interaction with BPG. D. Salt bridges are formed with N-terminal carbamates in deoxyhemoglobin. E. Salt bridges are formed between acidic and basic side chains of...

Questions 19-20 19. Which of the following factors INCREASES hemoglobin’s affinity for oxygen? [MARK ALL THAT...

Questions 19-20 19. Which of the following factors INCREASES hemoglobin’s affinity for oxygen? [MARK ALL THAT APPLY] a. decreased [H+ ] b. decreased temperature c. decreased PO2 d. decreased pH e. increased PCO2 20. You discover a new mutation in the gene coding for carbonic anhydrase. You observe that patients with this mutation exhibit: a. less buffering capacity of the blood d. higher PCO2 levels in blood b. less bicarbonate [HCO3-] concentration in blood e. Hb has a lower...

Which molecule binds oxygen better, myglobin or hemoglobin? Why are these relative affinities important in oxygen...

Which molecule binds oxygen better, myglobin or hemoglobin? Why are these relative affinities important in oxygen delivery to the body?

Subjects