Question

Briefly describe the role Dendritic cells play in bringing the virus to a lymph node.

Answer 1

The main role of the DCs in the viral infections is to activate naive that is antigen-specific CTLs in the lymph node. Following the conversion of naive CTLs into effector cells, these migrate into the tissues, where they actively contribute to reducing the number of infected cells, such as keratinocytes in them and CTLS are activated by dendritic cells.

Dendritic cells (DCs) are antigen-presenting cells (also known as accessory cells) of the mammalian immune system. Their main function is to process antigen material and present it on the cell surface to the T cells of the immune system in the LYMPHATIC SYSTEM and in lymph nodes. They act as messengers between the innate and the adaptive immune systems.

Dendritic cells are potent antigen presenting cells endowed with the unique ability to prime T-cell responses that are present in lymph nodes of our human body . To present foreign antigens to na ive T cells, dendritic cells must migrate from inflamed or injured peripheral tissues to the closest draining lymph nodes through afferent lymphatic vessels