Question

One page (on Word, about 400 words) summary of cardiac tissue engineering.

Please don't send in handwritten answers since they are hard to read.

Answer 1

Cardiac tissue engineering (CTE) aims to create contractile tissues to replace damaged or missing myocardial tissues.

Tissue engineering has been considered the ideal strategy for regenerative medicine in cardiology as heart has limited capacity of regeneration and increasing number of heart diseases.

It is an interdisciplinary field combining many techniques that aim to maintain, regenerate or replace a tissue or organ.

The main approach of cardiac tissue engineering is to create cardiac grafts, either whole heart substitutes or tissues that can be efficiently implanted in the organism, regenerating the tissue and giving rise to a fully functional heart, without causing side effects, such as immunogenicity.

It includes biomedical, biotechnological and engineering techniques.

cardiac tissue engineering strategies focus on temporary polymer scaffolds with adjustable degradation rates, good porosity, biocompatibility and elastomeric properties, which can mechanically favor the tissue contraction inherent to the cardiac function.