Question

In: Chemistry

What do tyrosinase inhibitors do? What is the importance of tyrosinase and tyrosinase inhibitors in the...

What do tyrosinase inhibitors do?
What is the importance of tyrosinase and tyrosinase inhibitors in the food industry?

Solutions

Expert Solution

Tyrosinase is an oxidase that is the rate-limiting enzyme for controlling the production of melanin. It is mainly involved in two distinct reactions of melanin synthesis; firstly, the hydroxylation of a monophenol and secondly, the conversion of an o-diphenol to the corresponding o-quinone. o-Quinone undergoes several reactions to eventually form melanin.Tyrosinase is a copper-containing enzyme present in plant and animal tissues that catalyzes the production of melanin and other pigments from tyrosine by oxidation, as in the blackening of a peeled or sliced potato exposed to air. It is found inside melanosomes which are synthesised in the skinmelanocytes. In humans, the tyrosinase enzyme is encoded by the TYR gene.

In food industry, tyrosinase inhibition is desired a tyrosinase catalyzes the oxidation of phenolic compounds found in fruits and vegetables into quinones, which gives an undesirable taste and color and also decreases the availability of certain essential amino acids as well as the digestibility of the products. As such, highly effective tyrosinase inhibitors are also needed in agriculture and the food industry


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