Receptor Tyrosine Kinases and Ras
a. Describe the events that occur upon ligand binding to
receptor kinase receptors.
b. Describe the similarities and differences in the cycling of
Gs and Ras between the active and inactive forms.
c. Describe the kinase cascade that transmits signals down from
activated Ras.
Which of the following consequences of a signaling molecule
binding to its receptor is NOT a short-term response?
chromatin remodeling, resulting in transcriptional changes
ubiquitination of a target protein, resulting in its
degradation
phosphorylation by a kinase
cAMP binding and protein activation
1. The insulin receptor is:
A. a metabolite receptor
B. a receptor tyrosine kinase.
C. a GPCR
D. a gasotransmitter
E. a second messenger
2. Which of the following reactions requires a Vitamin
B12 cofactor?
A. beta-oxidation of 18:0
B. beta-oxidation of (18:1 delta 9)
C. beta-oxidation of (16:2 delta 9 delta 12)
D. complete oxidation of (19:0)
E. all of these require Vitamin B12
3. Metabolite receptors bind to
___________________.
A. second messengers
B. DNA
C. GPCRs
D. Protein...
binding of epinephrine to its receptor sends a message into the
cells and stimulates the second messenger cAMP. once the fight or
flight response is no longer needed, cAMP is broken down by the
enzyme phosphodiesterase. caffeine blocks the enzyme
phosphodiesterase. explain why caffeine produces an energetic
feeling
23) After insulin or a growth factor such as EGF or
PDGF binds to its receptor and the receptors form a dimer, what is
the next immediate event?
a. Adaptor proteins binds to the receptor due to a conformational
change.
b. The dimerized receptor acts as a kinase to phosphorylate one or
more tyrosine residues on its dimerized partner.
c. The dimerized receptor acts as a kinase yo phosphorylate one or
more serine or threonine residues on its dimerized partner....