How the body gets rid of fluid if you have received way more saline fluid that...

How the body gets rid of fluid if you have received way more saline fluid that you need and how your body restores homeostatic water balance?

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Answer

Increased saline and water in the body increases blood volume leading to increased blood pressure.
Increased blood pressure cause atrial stretch that acts as a stimulus for the release of hormone atrial natriuretic peptide (ANP) from the atria.
This hormone triggers a negative feedback mechanism.
ANP directly acts on distal convoluted tubule of the nephron. It inhibits reabsorption of the NaCl antagonizing the effect of alsosterone.
As sodium reabsorption is inhibited, water reasborption is also reduced due to decrease in osmotic gradient.
ANP also acts on posterior pituitary gland to inhibit the release of anti-diuretic hormone.
Unavailability of ADH makes collecting duct of nephron impermeable to water.
Water cannot be retained and the volume of urine increases.
Loss of water in urine, reduce fluid volume from the body. The blood pressure becomes normal.
After retroration of homeostatis, ANP release from atria is inhibited.
In this way, the body restores homeostatic water balance.

Sydney Mullin answered 10 months ago

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