In: Statistics and Probability
Evidence on the efficacy of acupuncture for reducing the pain.
Design: Randomized, controlled trial.
Setting: Two outpatient clinics (an integrative medicine facility and a rheumatology facility) located in academic teaching hospitals and 1 clinical trials facility.
Patients: 570 patients(mean age [±SD], 65.5±8.4 years).
Intervention: 23 true acupuncture sessions over 26 weeks. Controls received 6 two-hour sessions over 12 weeks or 23 sham acupuncture sessions over 26 weeks.
Participants in the true acupuncture group experienced greater improvement in WOMAC function scores than the sham acupuncture group at 8 weeks (mean difference, 2.9 [95% CI, 5.0 to 0.8]; P 0.01) but not in WOMAC pain score (mean difference, 0.5 [CI, 1.2 to 0.2]; P 0.18) or the patient global assessment (mean difference, 0.16 [CI, 0.02 to 0.34]; P> 0.2). At 26 weeks, the true acupuncture group experienced significantly greater improvement than the sham group in the WOMAC function score (mean difference, 2.5 [CI, 4.7 to 0.4]; P 0.01), WOMAC pain score (mean difference, 0.87 [CI, 1.58 to 0.16]; P 0.003), and patient global assessment (mean difference, 0.26 [CI, 0.07 to 0.45]; P 0.02).
Limitations: At 26 weeks, 43% of the participants in the education group and 25% in each of the true and sham acupuncture groups were not available for analysis.
Conclusions: Acupuncture seems to provide improvement in function and pain relief as an adjunctive therapy.
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