What anitsera agglutinates Blood types: A negative, B positive and AB negative?

Solutions

Expert Solution

1.A negative antisera-B positive

A negative will have Antigen A on the surface of RBC and no Rh antigen. The plasma will have antibody B.

Agglutination is the clumping of the RBCs due to the action of Antigen-Antibody.The antigen is present on the surface of the RBCS, and the antibody will be present in the plasma.A particular blood group is the presence of the corresponding antigen on the RBC surface.i.e. A blood group will have antigen A on its RBC surface.

But, the antibody present in the plasma will be just opposite to the antigen type i.e.A blood group will have B antibody in the plasma.

Presence of Rh additional antigen on the surface of the RBC determines its Positive, and the absence is negative.

Agglutination occurs when a particular antigen will mix up with the same type antibodies.

So the antisera to form agglutination with A blood should have Antibody A in the plasma.Hence the antigen present on the RBC surface will be B. Hence B is the blood group.Since there is no Rh antigen no need of the Rh antibody in the plasma.Hence without Rh antibody blood will be having Rh antigen on the RBC surface. i.e.B positive

2.B positive antisera - A negative (Follow the 1st answer concept in this scenario)

3.AB negative antisera - O positive

In case of AB negative, the Antigens present are A & B(Since negative; no Rh antigen).So the plasma of antisera should contain both A & B Antibodies. Which is present in O blood group (No both the antigen on RBC).

Since no Rh antigen is present in the sample,the sample plasma contains Rh antibody.To make it agglutinate the antisera should contain Rh antigen. i.e O positive

Sydney Mullin answered 11 months ago

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