Explain the pathway that stimulates the release of aldosterone. (chapter on urinary system)

Expert Solution

By the RAS system they regulate the aldosterone release
Intially with the stimulation of JG apparatus in the kidney by decreased renal blood flow cause the release of renin from the JG cells.
The released renin is utilised for converting angiotensinogen produced by the liver to angiotensin I
The surface of pulmonary and renal endothelium contains angiotensin converting enzyme which positively helps in conversion of angiotensin I to angiotensin II
Angiotensin II causes adrenal cortex of adrenal gland to secrete aldosterone
The produced aldosterone acts by regulating potassium secretion and sodium reabsorption by acting primarily on principle cells of renal.tubules
It stimulates sodium potassium ATPase pump present on the basal lateral side, thus increasing permeability of sodium ions
Thus it increases sodium and water reabsorption and also increases potassium excretion
That can cause water to retain in the body thereby increasing blood volume and pressure.

Sydney Mullin answered 1 year ago

_____ stimulates release of aldosterone and antidiuretic hormone, which decrease water excretion A) Renin B)angiotensin II

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