In: Anatomy and Physiology
Based on the ion concentrations provided in the table below, which of the following would result in an EPSP? Select all that apply.
Ion | Intracellular fluid | Extracellular fluid |
[Na+] | 15mM | 140mM |
[K+] | 130mM | 4mM |
[Cl-] | 5mM | 120mM |
[Ca2+] | <0.001mM | 1.2mM |
A) Sodium channels open
B) Potassium channels open
C) Chloride channels open
D) Calcium channels open
a) Sodium channels open
d) calcium channels open
Explanation: Opening of sodium channels result in influx of positive charge Na+ ion from their higher extracellular concentration into the lower intracllular concentration leading to decrease in negative potential of the membrane. (EPSP).
Opening of chloride channels result in influx of negative charge Cl- ion from their higher extracellular concentration into the lower intracellular concentration leading to increase in the negative potential of the membrane. (IPSP)
Opening of calcium channels result in influx of positive charge Ca++ ion from their higher extracellular concentration into the lower intracllular concentration leading to decrease in negative potential of the membrane. (EPSP).
Opening of potassium channels result in efflux of positive charge K+ ion from their higher intracellular concentration into the lower extracllular concentration leading to increase in negative potential of the membrane.(IPSP)