In: Anatomy and Physiology
Compare the cause and effects of Cushing’s syndrome and Addison’s disease.
cuase | ||
Cushing's syndrome | it is marked by excessive levels of cortisol & this can be caused by eexternal forces such as glucocorticoid therapy or internal forces such as tumor producing adenocorticotropic hormone ( ACHT) causing excess cortisol production. | |
addison's disease | it is cuased by low levels of cortisol & aldosterone.disease is usually caused by autoimmune disease that damage the adrenal gland. |
effects | |
Cushing's syndrome | generalized muscle weakness and wasting...moon face and buffalo hump ,,,trunkal obesity within the extremities,,supraclavicular fat pads and obesity...hyperglycemia, hyperthermia,,,hypokalemia, hypercalcemia,,hypertension, fragile skin that easily bruises reddish purple straiea on the abdomen and upper thighs....hirsturism (is only seen in females that is masculine characteristics) |
addison's disease | muscle weakness, lethargy,fatigue ...gastrointestinal distabence,,weight loss,,menstrual changes in women,impotence in men...hypoglycemia,,hypothermia,,,hyperkalemia,,,hypercalcemia,,postural hypotension ,,,hyperpigmentation of the skin ( bronzed) with primary disease. |