Question

What are some diseases or genetic abnormalities caused by dominant genes? Why are severe dominant genetic diseases rarer than recessive ones?

Answer 1

Examples of dominant genetic disorders are: Huntington's ailment (or Huntington’s chorea), neurofibromatosis, hypercholesterolemia and polycystic kidney ailment.

Severe and early autosomal dominant illnesses are rarer than recessive autosomal sicknesses because on this last organization the affected allele may be hidden in heterozygous individuals and transmitted to the offspring till becoming homozygous (the real manifestation of the disorder). In intense dominant sicknesses, the heterozygous character presents the situation and frequently dies without having offspring. (a few genetic sicknesses appear later, consisting of Huntington ailment; in these cases, the incidence is better because many people have children earlier than understanding that they are companies of the dominant gene).

Examples of recessive genetic disorders are: cystic fibrosis, albinism, phenylketonuria, galactosemia and Tay-Sachs disorder.