Polydactyly is a rare genetic trait resulting in extra fingers caused by a dominant allele, P....

Polydactyly is a rare genetic trait resulting in extra fingers caused by a dominant allele, P. A woman inherits the condition from her mother and marries an unaffected man with no family history of the disease.

Draw this pedigree and label the genotype for every family member.

What is the probability that their first child will be a daughter AND be unaffected?

Expert Solution

Answer

Polydactyly is an autosomal dominant disease cause by dominant allele P

Polydactyly allele dominant : P

recessive allele : p

Mother of women : Pp (genotype)

Woman genotype : Pp (Polydactyly)

Man genotype : pp (normal condition)

Cross between woman (Pp) and man (pp)

	P	p
p	Pp (Polydactyly)	pp (Normal/ unaffected)
p	Pp (Polydactyly)	pp (Normal / unaffected)

The probability of child with polydactyly is 1/2

The probability of having unaffected child is 1/2

The probability of having first child is daughter is 1/2

So, the probaility of having first child will be a daughter AND be unaffected is 1/2 (daughter) X 1/2 (unaffected) = 1/4

gladiator answered 2 years ago

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