Protein catabolism can produce acetyl-CoA. Explain how high protein diets could lead to an increase in...

Protein catabolism can produce acetyl-CoA. Explain how high protein diets could lead to
an increase in body fat percentage.

Expert Solution

After catabolism protein is converted intto acetyl-CoA, this aetyl-CoA enters into krebs cycle and or participate into liogenesis to form fat and increase body fat percentage. Acetyl‐CoA is used as the precursor for fatty acid synthesis. Acetyl-CoA modified into malonyl-CoA and provide the carbons to growing fatty acid chain.come from the Acetyl group of acetyl‐CoA provide all formation of malonyl-CoA is occur by acetyl‐CoA by the addition of CO2 with the help of enzyme acetyl‐CoA carboxylase. Synthesis of fatty acid by acetyl-CoA is described in attached figure.

Further, fatty acid chain elongation takes place and it elongate up to 16 carbons are or more. This process occurs in endoplasmic reticulum. Now, synthesized fatty acids are ready to store in adipose tissues. This way, protein helps to increase the body fat percentage.

gladiator answered 1 year ago

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