Propose three potential fates of the acetyl CoA generated from catabolism of branched chain amino acids.

Expert Solution

The potential fates of Acetyl co-A are:

1. They enter into the Krebs cycle which takes place in the matrix of mitochondria. Various enzymes are involved in the Krebs cycle. Krebs cycle is an aerobic process. Acetyl Co-A is accepted by Oxalo acetate(a four carbon compound). They result in the first product of Krebs cycle, Citric acid , which is a 6C compound. This process ultimately oxidizes Acetyl co-A into carbon dioxide and water.

2. In Mitochondria, ketone bodies are synthesized from Acetyl co-A. These ketone bodies are used for energy production in liver and other tissues. Excess ketones are produced when there is lack of glucose ,for example during starvation.

3. Acetyl co-A can be used for formation of cholesterol or other fatty acids in the cytoplasm. It usually occurs when the cell has enough energy to perform other functions.

gladiator answered 1 year ago

Identify ketogenic and glucogenic amino acids and their pathways to produce acetyl CoA or glucose respectively...

Identify ketogenic and glucogenic amino acids and their pathways to produce acetyl CoA or glucose respectively (enzymes are not necessary) (20 points).

2. Describe the mechanism by which muscle tissue uses branched-chain amino acids as fuel and passes...

2. Describe the mechanism by which muscle tissue uses branched-chain amino acids as fuel and passes the nitrogen from these amino acids to liver tissue to be converted to urea. Please offer detailed explanations. Thank you.

To enhance gluconeogenesis using acetyl CoA from the oxidation of fatty acids, the normal TCA cycle...

To enhance gluconeogenesis using acetyl CoA from the oxidation of fatty acids, the normal TCA cycle is turned off by phosphorylation of ___ and the glyoxylate cycle is turned on, instead. This cycle uses two acetyl-CoA to produce one ___ , which is also substrate for gluconeogenesis. Select one: a. isocitrate dehydrogenase ; oxaloacetate b. isocitrate lyase ; citrate c. isocitrate dehydrogenase ; citrate d. isocitrate lyase ; oxaloacetate e. None of these

Compare the shuttle systems for transporting fatty acids into the mitochondria and acetyl-CoA into the cytosol.

Protein catabolism can produce acetyl-CoA. Explain how high protein diets could lead to an increase in...

Protein catabolism can produce acetyl-CoA. Explain how high protein diets could lead to an increase in body fat percentage.

Two of the facts which differentiate lipids and carbohydrates from amino acids are that, amino acids...

Two of the facts which differentiate lipids and carbohydrates from amino acids are that, amino acids can neither be stored nor excreted. true false A baby got sick a few weeks after birth and test results show that the baby had higher than normal levels of the amino acid phenylalanine. Which of the following best describes the baby's probable diagnosis? The baby has maple syrup disease The baby has PKU More lab test are needed to confirm the cause malady...

What percentage of carbon atoms in cholesterol are derived from acetyl-coA?

In glycolysis, the conversion from pyruvate to acetyl CoA is irreversible, but I found that during...

In glycolysis, the conversion from pyruvate to acetyl CoA is irreversible, but I found that during the synthesis of FA, acetyl CoA can be synthesized to citrate -> OAA -> Malate ->pyruvate when Citric acid shuttle, why we cannot say that pyruvate can turn back to acetyl CoA?

11. In the Pyruvate Dehydrogenase complex, the acetyl unit is passed to the coA directly from...

11. In the Pyruvate Dehydrogenase complex, the acetyl unit is passed to the coA directly from __________________. A. biotin B. TPP C. FAD D. pyruvate E. lipoyllysine 13. A common feature of molecules that signal through steroid and metabolite hormone receptors is: A. they are hydrophobic B. they are polar C. their receptors are mostly found in the cell surface membrane D. their receptors signal through second messengers. E. their...

Which of the following amino acids has a side chain that can serve as a hydrogen...

Which of the following amino acids has a side chain that can serve as a hydrogen bond donor (but not acceptor) in its predominant form at pH 7? D K M V N

Question