Answer
Hormone is a chemical messenger released from
an endocrine gland directly into blood stream that binds to
receptors on a target cell.
- Endocrine system consist of endocrine glands and their
secretions (hormones).
- Hormones function to regulate biological processes such as
metabolism and cellular functions.
Working of hormones :
- Usually hormones are secreted triggered by a hormonal
or neural stimulus.
- Regulating hormones (secreted by hypothalamus) triggers
released of tropic hormones (from anterior pituitary) that binds to
target endocrine glands and stimulate release of hormone from
target glands.
Example : Corticotropin releasing hormone
stimulates release of adrenocorticotropic hormone which in turn
stimulates cortisol release.
- Hormone secretions are mostly regulated by negative feedback
mechanism in order to main homeostasis.
- There are some direct acting hormones that binds to target
cells and stimulate desired physiological response.
Example : Oxytocin stimulate uterine
contractions.
There are two types of hormones :
1) Peptide hormones : They contain receptors on
the cell membrane. They require a second messenger to initiate
cellular response.
2) Steroid hormones : They can cross plasma
membrane and bind to receptors in cell nucleus to inititate gene
trasncription.