Question

1 (a). Describe one fundamental way in which proteins and DNA resemble one another and one fundamental way in which they differ from one another.

(b). Using the genetic code table provided in lecture (or you can see one here: http://tigger.uic.edu/classes/phys/phys461/phys450/ANJUM02/codon_table.jpg) write the sequence of a mRNA molecule that could encode the following amino acid sequence (for amino acids that are specified by more than one codon, just choose one of the codons; label 5’ and 3’ ends in all figures):

methionine-leucine-valine-lysine-serine-tryptophan-threonine.

(c). Write both strands of the DNA molecule from which this mRNA was transcribed.

(d). Delete the second base of the leucine codon in the mRNA and retranslate your mRNA.

Answer 1

Answer a]

Fundamental ways in which DNA & protein resemble one another=

1]DNA & proteins both consists of Carbon,Hydrogen,Oxygen,nitrogen,phosphorus

Fundamental ways in which DNA & protein differ fromone another as:

structure of DNA consists of a phosphate group which gives negative charge to DNA.

it also consists of a nitrogen base i.e. Adenine ,thymine,guanine & cytosine.

consists of a 5 carbon sugar.

the building block is ribonucleotides

Proteins= the building block is amino acids

amino acids are joined with each other by means of peptide bond forms the protein structure.

In DNA genetic information is stored in the form of codons.that translated into proteins.

b] The sequence of a mRNA molecule that could encode the following amino acid sequence

methionine-leucine-valine-lysine-serine-tryptophan-threonine. IS AS FOLLOWS :

5' AUG - CUU- GUU - AAA - UCU- UGG - ACU 3'--------------mRNA

(c). Both strands of the DNA molecule from which this mRNA was transcribed is

5' AUG - CUU- GUU - AAA - UCU- UGG - ACU 3'--------------mRNA

3' TACGAACAATTTAGAACCTGA 5'--------------two strands of DNA

5' ATGCTTGTTAAATCTTGGACT 3'-----------

(d). By Deleting the second base of the leucine codon in the mRNA and retranslate your mRNA.

methionine-leucine-valine-lysine-serine-tryptophan-threonine. IS AS FOLLOWS :

5' AUG - CUU- GUU - AAA - UCU- UGG - ACU 3'--------------original mRNA

when we delete second base of leucine codon then,

5' AUG - CUG -UU A AAU CUU GG A CU 3'

5'Methionine-leu -stop -3'------------protein