In: Biology
Research 2 examples of cell communication in the human body. For each example identify the following components of the signaling pathway: signal, receptor, messengers, output effects
Example 1: Acetyl choline signalling pathway in synapses(paracrine pathway)
Signal : Action potential travelling through the neuron reaches the axon terminal, there is depolarisation and opening up of voltage gated calcium channels and influx of calcium
Messenger : Acetyl choline stored in the synaptic vesicles in terminal end of axon
Receptor :Acetyl choline receptors on muscles
Output effect :Muscle contraction
Example 2 : Insulin signalling pathway (endocrine pathway)
Signal :Increased blood glucose binds to GLUT 2 receptors in pancreatic beta cells and causes closing of potassium channels and opening of calcium channels which further causes release of insulin
Messenger : Insulin released from pancreatic beta cells
Receptor :Insulin receptor tyrosine kinase in liver, muscle, adipose tissue
Output effect : Conversion of glucose to glycogen in liver, glucose to fat in adipose tissue, glucose to amino acids.