Question

How would a dietary resin that absorbs bile salts reduce plasma cholesterol levels?

Answer 1

Cholesterol absorption happens principally in the duodenum and proximal jejunum of the small intestine and is subject to the nearness of bile salts. Without bile emission, or within the sight of bile acid-restricting resins, there is for all intents and purposes no intestinal absorption of cholesterol. Overall, people retain 50– 60% of the intestinal substance of cholesterol, however, there is a substantial between singular fluctuation in absorption, with values going from as low as 20% to as high as 80%. Intestinal transit time is identified with cholesterol absorption with slower transit times bringing about higher fragmentary absorption rates. Dietary factors that influence the relative percent absorption of cholesterol to incorporate the aggregate mass of dietary cholesterol, the centralization of plant sterols in the eating routine, and the sort and measure of dietary fibre. Studies recommend that the proportion of polyunsaturated to saturated fat (P:S) in the eating regimen has little impact on cholesterol absorption rates in people, nor does the measure of dietary fat.