Question

how is toxicity related in plasma binging

How do the levels of co2 and hco3 in blood differ in Respiratory acidosis (RA) and (Metabolic Acids)

Answer 1

The preclinical research suggests that the dataset which has mainly three classes of drugs ( acids, bases and neutrals). These also comes with LD50 values in mice which was analysed to investigate the possible linkage between the high plasma protein binding and acute toxicity. In the initial set, it was found that the high plasma protein binding and acute toxicity . Initially it was found to be with high plasma protein binding rhat associated with the toxicity for a ids and then neutrals. But after the compensation for differences in lipophilicity, plasma protein binding qas found not to be associated with toxicity.

The Respiratory alkalosis ( RA) is the most common acid base abnormality with no difference between genders.

HCO3 functions as an alkalotic substance where the CO2 functions as an acidic substance. The increase in HCO3 ir the decrease in CO2 will make the blood more alkalotic.