"A study was conducted to evaluate new test for human papilloma virus (HPV). One hundred fifteen...

"A study was conducted to evaluate new test for human papilloma virus (HPV). One hundred fifteen women with HPV were compared to 426 women who did not have HPV. A total of 97 women tested positive using the new test, 81 of whom really did have HPV.

You will be graded on calculations (including completion of the 2x2 table as shown in class and showing your work for calculation, your interpretations, and your answers to the other questions. Your interpretations must be specific and will be graded on accuracy, correct use of scientific terminology, professional writing style, grammar and spelling."

a) Complete a contingency table

b) How many women are in each of the following categories?

True positives:

False positives:

True negatives:

False negatives:

c) Calculate and interpret the sensitivity of the new screening test.

d) Calculate and interpret the specificity of the new screening test.

e) Calculate and interpret the positive predictive value of the new screening test.

f) Calculate and interpret the negative predictive value of the new screening test.

g) Do you think that it would be better to use this new screening test for HPV or an older screening test with 90% sensitivity and 80% specificity. The older screening test is more expensive. Write 75-100 words supporting your position.

Solutions

Expert Solution

orchestra answered 1 year ago

Next > < Previous

Related Solutions

Describe the biosynthesis of human papillomavirus (HPV). Discuss the transcription of the virus genome into new...

Describe the biosynthesis of human papillomavirus (HPV). Discuss the transcription of the virus genome into new virion particles. Make sure to include if your virus must package any special enzymes in order to be effective.

What evidence is there to indicate that the human papilloma virus (HPV) vaccine currently used in...

What evidence is there to indicate that the human papilloma virus (HPV) vaccine currently used in the UK (Gardasil) should be replaced with an alternative vaccine? Your answer should provide an argument that is in favour of this change, but should also consider the evidence against it.

A randomized experimental study was conducted to evaluate the effectiveness of a new cancer vaccine. One-thousand...

A randomized experimental study was conducted to evaluate the effectiveness of a new cancer vaccine. One-thousand healthy adults were randomized to receive either the new vaccine (500 adults) or the old vaccine (500 adults). The adults were followed for 10 years to monitor the incidence of colon cancer. At the end of the study, the risk ratio for developing colon cancer was 0.5 among the adults who received the new vaccine compared to adults who received the old vaccine. The...

A screening examination was performed on 250 persons for human papilloma virus (HPV), which is found...

A screening examination was performed on 250 persons for human papilloma virus (HPV), which is found in cervical cancer. A definitive diagnosis for cervical cancer among the 250 subjects had been obtain previously. There were 60 subject who tested positive for HPV who also had cervical cancer, 40 subjects who tested positive for HPV but did not have cervical cancer. There were 10 subjects who tested negative for HPV, but had cervical cancer and 140 subjects who tested negative for...

A very large trial was conducted to combat the Human Papillomavirus (HPV) on 402,245 consenting adults....

A very large trial was conducted to combat the Human Papillomavirus (HPV) on 402,245 consenting adults. 201,867 of the patients were given an experimental vaccine (the treatment group), and 200,378 of them were administered placebos (the placebo group). In the treatment group 41 people contracted HPV, and in the placebo group 124 people contracted HPV. a) Use a 5% significance level to test the claim that this vaccine is effective, and b) create a confidence interval for testing. (Follow all...

Human papilloma virus (HPV) is the most common sexually transmitted infection, with 45% of 20-24 yr...

Human papilloma virus (HPV) is the most common sexually transmitted infection, with 45% of 20-24 yr old women infected. Infection of the genitalia and cervix with HPV increases the risk of cervical cancer 10-fold. Two proteins encoded by HPV DNA bind to p53 and Rb. Which of the following do you think would Best describe the function of those two HPV proteins? proto-oncogenes oncogenes tumor suppressor gain of function mutant proteins

Fifteen subjects are sampled from a population of one hundred, one quarter of which have COVID-19....

Fifteen subjects are sampled from a population of one hundred, one quarter of which have COVID-19. What number of subjects in the sample does one expect to have COVID-19? Does the answer depend if the sampling is done with or without replacement? please show work...

In New York City, a study was conducted to evaluate whether any information that is available...

In New York City, a study was conducted to evaluate whether any information that is available at the time of birth can be used to identify children with special educational needs. In a random sample of 45 third-graders enrolled in the special education program of the public school system, 4 have mothers who have had more than 12 years of schooling. A) Construct a 90% CI for the population proportion of children with special educational needs whose mothers have had...

A study was conducted to explore the effects of ethanol on sleep time. Fifteen rats were...

A study was conducted to explore the effects of ethanol on sleep time. Fifteen rats were randomized to one of three treatments. Treatment 1 got only water (control). Treatment 2 got 1g of ethanol per kg of body weight, and treatment 3 got 2g/kg of ethanol. The amount of REM sleep in a 24hr period was recorded, in minutes. Data are below: Treatment 1: 63, 54, 69, 50, 72 Treatment 2: 45, 60, 40, 56 Treatment 3: 31, 40, 45,...

A study was conducted to explore the effects of ethanol on sleep time. Fifteen rats were...

A study was conducted to explore the effects of ethanol on sleep time. Fifteen rats were randomized to one of three treatments. Treatment 1 got only water (control). Treatment 2 got 1g of ethanol per kg of body weight, and treatment 3 got 2g ethanol per kg of body weight. The amount of REM sleep in a 24hr period was recorded, in minutes. Data are below: Treatment 1: 63, 54, 69, 50, 72 Treatment 2: 45, 60, 40, 56 Treatment...

Subjects