Question

In: Statistics and Probability

A screening examination was performed on 250 persons for human papilloma virus (HPV), which is found...

A screening examination was performed on 250 persons for human papilloma virus (HPV), which is found in cervical cancer. A definitive diagnosis for cervical cancer among the 250 subjects had been obtain previously. There were 60 subject who tested positive for HPV who also had cervical cancer, 40 subjects who tested positive for HPV but did not have cervical cancer. There were 10 subjects who tested negative for HPV, but had cervical cancer and 140 subjects who tested negative for HPV, who did not have cervical cancer. (Hint: create a 2 X 2 table). The specificity of this test is expressed as: I need the "specificity" of this test

Solutions

Expert Solution

specificty:

specificity identifies with the test's capacity to accurately dismiss sound patients without a condition .think about the case of a restorative test for diagnosing a sickness.specificity of a test is the extent of solid patients known not to have the malady ,who will test negative for it.

2X2 table:

disease no disease
test positive true positive false positive
test negative false negative true negative

from the given data substitute the values according to the above table

cervical cancer no carvical cancer
test positive 60(ture +ve) 40(false +ve)
test negative 10(false -ve) 140(true -ve)

now specificity is given by

specificity=true negative /total no. of postitivities

total no.of positivities=true positive + false negative

specificity=true negative/(true positive + false negative)

now substitute the values by using the above 2X2 table

then

specificity=140/(140+40)

=140/180

specificity=0.7777777

now percentage of specificity is given by

%specificiy=0.777777*100

%specificty=77.7777%


Related Solutions

A screening examination was performed on 250 persons for Factor X, which is found in disease...
A screening examination was performed on 250 persons for Factor X, which is found in disease Y. A definitive diagnosis for disease Y among the 250 persons had been obtained previously. The results of diagnoses are charted here: Test Results Disease Present Disease Absent Positive for Factor X 40 60 Negative for Factor X 10 140 Based on the information provided, which of the following expresses the sensitivity of this test? A) 30% B) 70% C) 56% D) 80% Based...
What evidence is there to indicate that the human papilloma virus (HPV) vaccine currently used in...
What evidence is there to indicate that the human papilloma virus (HPV) vaccine currently used in the UK (Gardasil) should be replaced with an alternative vaccine? Your answer should provide an argument that is in favour of this change, but should also consider the evidence against it.
Describe the biosynthesis of human papillomavirus (HPV). Discuss the transcription of the virus genome into new...
Describe the biosynthesis of human papillomavirus (HPV). Discuss the transcription of the virus genome into new virion particles. Make sure to include if your virus must package any special enzymes in order to be effective.
"A study was conducted to evaluate new test for human papilloma virus (HPV). One hundred fifteen...
"A study was conducted to evaluate new test for human papilloma virus (HPV). One hundred fifteen women with HPV were compared to 426 women who did not have HPV. A total of 97 women tested positive using the new test, 81 of whom really did have HPV. You will be graded on calculations (including completion of the 2x2 table as shown in class and showing your work for calculation, your interpretations, and your answers to the other questions. Your interpretations...
Human papilloma virus (HPV) is the most common sexually transmitted infection, with 45% of 20-24 yr...
Human papilloma virus (HPV) is the most common sexually transmitted infection, with 45% of 20-24 yr old women infected. Infection of the genitalia and cervix with HPV increases the risk of cervical cancer 10-fold. Two proteins encoded by HPV DNA bind to p53 and Rb. Which of the following do you think would Best describe the function of those two HPV proteins? proto-oncogenes oncogenes tumor suppressor gain of function mutant proteins
Which of the following is not a characteristic of the human immunodeficiency virus?   A. long incubation...
Which of the following is not a characteristic of the human immunodeficiency virus?   A. long incubation period;   B. reverse transcriptase;   C. broad host range;   D. high rates of mutation and genetic variability.
What are the various routes by which transmission of human immune deficiency virus takes place?
What are the various routes by which transmission of human immune deficiency virus takes place?
Compared virus sequences with human and avian. they are over 95%similiar. Based on your results (which...
Compared virus sequences with human and avian. they are over 95%similiar. Based on your results (which of course are limited—it would be necessary to do many more comparisons in reality), do you think there is evidence that human adaptation is occurring in H5N1 viruses that might merit concern about human-to-human transmission in the near future?
If an enzyme found in human cells would be affected by Sofosbuvir, which eukaryotic enzyme would...
If an enzyme found in human cells would be affected by Sofosbuvir, which eukaryotic enzyme would it most likely affect? a) DNA Polymerase b) RNA Polymerase c) Telomerase d) Reverse Transcriptase Thank you!
What are two adaptations found in the HUMAN hand which make our hands so useful for...
What are two adaptations found in the HUMAN hand which make our hands so useful for grasping tools? At least 5+ complete sentences. thank you for your help!
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT