In: Chemistry
what are the starting reactants and final products of TCA Cycle....the number of coenzyme reduced and where it occurs
The starting material of the TCA cycle is acetyl coA NAD+, FAD, ADP, Pi and 3H2O.
The final products of the TCA cycle are carbon dioxide, reduced coenzymes (FADH2 and 3NADH) and ATP.
Reaction :
Acetyl CoA + 3NAD+ + FAD + ADP + Pi + 3H2O ----> 2CO2 + CoA + FADH2 + 3NADH + ATP + 3H+
The number of coenzymes reduced/one cycle in mitochondrial matrix :
a) NAD+ ----> NADH - 3
b) FAD -----> FADH2 - 1
Ubiquinone (Q) ----> Reduced Ubiquinone (QH2)
Reactions are :
Isocitrate + NAD+ -----> alpha ketoglutarate + NADH
alpha ketoglutarate + NAD+ ----> succinyl coA + NADH
Succinyl coA + ADP ----> Succinate + ATP
Succinate + FAD ----> Fumarate + FADH2
Malate + NAD+ ----> oxaloacetate + NADH