What is the Transition Reaction? What is the substrate? What are the products? What is Coenzyme A?

What is the Transition Reaction?

What is the substrate? What are the products?

What is Coenzyme A?

Solutions

Expert Solution

Chemically transition reaction is termed as oxidative decarboxylation. However commonly it is known as transition reaction because it acts as a transition(connects) between the glycolysis reaction and the krebs cycle.In this reaction two molecules of the 3-carbon pyruvate from glycolysis and other pathways are converted into two molecules of the 2-carbon molecule acetyl Coenzyme A and 2 molecules of carbon dioxide. Here , a carboxyl group of each pyruvate is removed as carbon dioxide and then the remaining acetyl group combines with coenzyme A (CoA) to form acetyl-CoA.

Reactants -2 pyruvate 2 NAD+ 2 coenzyme A

Products 2 acetyl-coA 2 NADH 2 CO2

Coenzyme A is an essential, universally distributed, thiol-containing cofactor which works as the major acyl group carrier in all cells. It is primarily known for its role in synthesis and oxidation of fatty acids and activation of pyruvate in the citric acid cycle

gladiator answered 1 year ago

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