What would happen to an Action Potential if voltage-gated K+ channels were blocked? A. the Action...

What would happen to an Action Potential if voltage-gated K⁺ channels were blocked?

	A.	the Action Potential could not occur
	B.	the Action Potential would not repolarize
	C.	the height of the action potential would be reduced
	D.	the undershoot (after-hyperpolarization) would not occur

Expert Solution

Activation leads to an increase in conductance and the termination of action potentials, hyperpolarization, and a reduction in excitability. Conversely, a block of the channels leads to depolarization, prolongation of action potentials, repetitive firing, and increases in transmitter release and endocrine activity.

Potassium channels are also responsible for repolarizing slow-response action potentials in the sinoatrial and atrioventricular nodes. Therefore, blocking these channels slows (delays) repolarization, which leads to an increase in action potential duration and an increase in the effective refractory period (ERP).

So, option B( the Action Potential would not repolarize ) is the correct answer.

gladiator answered 2 years ago

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