Describe the relationship between voltage-gated ion channels and the steps of generating an action potential.

Expert Solution

- Action potential is a transient change in the membrane potential of about 100 mV (from -70 mV to +35 mV), which is conducted along the axon in all or none fashion. Voltage gated ion channels are involved in action potential (mainly voltage gated sodium and potassium channels).
- Phase of local potential : It occurs due to opening of few voltage gated sodium channels (Na+ channels). In this, the membrane potential rises from -70 mV (resting membrane potential) to -55 mV.
- Phase of depolarization : It occurs due to sodium ions influx due to opening of large number of voltage gated sodium channels which raises the membrane potential from -55 mV to +35 mV.
- Phase of repolarization : It occurs mainly due to potassium efflux due to increased exit of potassium ions from the voltage gated potassium channels as well as inactivation of sodium channels. The membrane potential falls from +35 mV to -70 mV.
- Phase of after hyperpolarization : It occurs due to slow return of potassium channels to the closed state and the membrane potential falls beyond -70 mV ( i.e the membrane potential falls below the resting membrane potential of -70 mV).
- The entire process of action potential takes about 1 msec.

Sydney Mullin answered 10 months ago

Describe the importance of voltage-gated channels in the conduction of an action potential.

What would happen to an Action Potential if voltage-gated K+ channels were blocked? A. the Action...

What would happen to an Action Potential if voltage-gated K+ channels were blocked? A. the Action Potential could not occur B. the Action Potential would not repolarize C. the height of the action potential would be reduced D. the undershoot (after-hyperpolarization) would not occur

Describe and explain the functions and locations of various voltage-gated K+ ion channels.

Describe the role of voltage gated sodium channels in action potentials that travel along the sarcolemma.

Are voltage gated sodium channels, and voltage gated potassium channels considered secondary active transporters? If not...

Are voltage gated sodium channels, and voltage gated potassium channels considered secondary active transporters? If not then what are they called, and could you please explain what a secondary active transporter is and include a common example of one?

Describe the two stages of the Action Potential. Include (i) the names of the ion channels...

Describe the two stages of the Action Potential. Include (i) the names of the ion channels and whether they are active or passive, (ii) which of these ion channels open during the first stage and which open during the second stage, and the direction ions move, and (iii) the value in mV reached during the two stages.

Tetrodotoxin is a molecule that blocks voltage-gated sodium ion channels. What would happen if a neuron...

Tetrodotoxin is a molecule that blocks voltage-gated sodium ion channels. What would happen if a neuron was exposed to tetrodotoxin? Specify the effect of tetrodotoxin on the communication capacity of a neuron. Give a detailed answer by describing the role of sodium ions in producing the action potential. Help please

1. What would happen if there were a blockage to voltage-gated Na+ channels during an action...

1. What would happen if there were a blockage to voltage-gated Na+ channels during an action potential? 2. What would occur to an action potential if there was delayed inactivation of voltage-gated Na+ channels? 3. What would happen to an action potential when a toxin prevents ACh binding to nAChRs on muscle fibres? 4. What would happen to an action potential if a toxin which forms pores in the cell membrane of neurons, allowing the influx of Ca2+ into the...

QUESTION 1 What letter corresponds to the phase in which voltage-gated Na+ channels are open? action...

QUESTION 1 What letter corresponds to the phase in which voltage-gated Na+ channels are open? action potential.pdf A. B. C. D. E. QUESTION 2 Which of the following statements is true about the mRNA whose structure is depicted in the diagram shown below? mRNA schematic.pdf A.This could be a primary transcript from a prokaryote. B. This could be a primary transcript from a eukaryote but not a prokaryote. C. This could be a mature mRNA from a eukaryote but not...

Relate each phase of an action potential with the function of relevant ion channels..

Question