In: Chemistry
Calculate the overall percent yield of the synthesis to produce crude lidocaine. 3.0ml of 2,6-dimethylaniline and 2.0ml of alpha-chloroacetyl was used to produce 8.349g of alpha chloro 2,6 dimethylacetanilide. 7.5 ml diethylamine was added to the alpha chloro 2,6 dimethylacetanilide and 2.391g of crude lidocaine was produced
The overall yield can be obtained by calculating the yield of both steps as follows.