7. What are the different concerns about off-target edits by CRISPR-Cas when editing the human genome...

7. What are the different concerns about off-target edits by CRISPR-Cas when editing the human genome in embryos versus adult somatic cells?

Solutions

Expert Solution

when the gene is edited in the the somatic cell of an individual by CRISPR- Cas method, then it is found to be the restricted action in the somatic cell of a particular region in the body only. The whole individual do not Express such genes. And it cannot pass the the gene to the offspring.

But when the gene is edited in the embryonic stages, then the gene is found in all cells of the body. Because embryo will divide further to produce whole individual. That's why the modified cells are found in the whole body parts. It is also expressed in germ cell region. That's why an individual can pass the genes to the next generation too.

gladiator answered 1 year ago

Next > < Previous

Related Solutions

What is a single guide RNA, and what role does it play in CRISPR-Cas genome editing...

What is a single guide RNA, and what role does it play in CRISPR-Cas genome editing in eukaryotic cells?

To differentiate between the host genome and the pathogen to target for elimination in the CRISPR-Cas...

To differentiate between the host genome and the pathogen to target for elimination in the CRISPR-Cas 9 system a. a protospacer adjacent motif (PAM) must follow the protospacer b. the spacers must be interspersed with CRISPR c. the spacers must be sequenced in order of previous contact with a pathogen d. the spacer regions must base pair with target sequences CRISPR-Cas gene editing systems require a series of sequences that permit mutation, knock-out, or knock-in capabilities. Select the required sequence...

3) Suggest three major potential reasons for off-target effects using the CRISPR/CAS system in gene editing.

What are the benefits of the human genome project? What are some ethical and legal concerns?...

What are the benefits of the human genome project? What are some ethical and legal concerns? How do you feel about genetic research?

what are 8 pro facts and 8 con facts about gene editing and CRISPR-Cas9. Moreover, would...

what are 8 pro facts and 8 con facts about gene editing and CRISPR-Cas9. Moreover, would you agree that CRISPR-Cas9 gene editing in human embryos would have a positive outcome?

1. what is genome sequencing? what do we now know about the human genome from sequencing...

1. what is genome sequencing? what do we now know about the human genome from sequencing it? 2. explain different applications of genomics. What are SNPs is and how are they useful? 3. what are the uses of biotechnology in medicine?

7. What is the primary trade-off that an accountant must consider when deciding whether to identify...

7. What is the primary trade-off that an accountant must consider when deciding whether to identify cost drivers? Is the cost/benefit of the process reasonable for more accurate cost behavior obtained. Will the cost driver identification provide different costs for different purposes. Will material related drivers be more accurate than labor-related drivers. Will the cost relationship be to complex to understand. There is no trade-off to consider using cost drivers.

When thinking about the process of actually constructing a logic model, what are the different forms...

When thinking about the process of actually constructing a logic model, what are the different forms that one could take? How might logic models differ visually from program or project?

Subjects