Question

In: Biology

Which of the following mutations would promote malignancy in cells whose proliferation is inhibited by TGFBeta?...

Which of the following mutations would promote malignancy in cells whose proliferation is inhibited by TGFBeta? a) Dominant negative SMAD4 b) Loss of TGF Beta receptor II c) Overexpression of Smad2

Explain why it is correct and why the other options are wrong.

Solutions

Expert Solution


Related Solutions

What are the conditions that promote proliferation of parasitic protozoans?
What are the conditions that promote proliferation of parasitic protozoans?
Mutations in which cells are inherited? A)Somatic cells B)Reproductive cells? Which type of selection do drives...
Mutations in which cells are inherited? A)Somatic cells B)Reproductive cells? Which type of selection do drives antibiotic resistance in hospitals? A)Directional B)Stabilizing C)Disruptive What does fitness measure (in biology)? A.Physical strength B.Number of offspring that survive C.Life span D.Body fat index Would you expect humans to have matched the criteria for altruism in the distant past? A) yes B)no Would you expect humans to have matched the criteria for altruism out on the street today? A) yes B)no Stuck on...
which of the following would indicate the beginning of cytokinesisin plant cells
which of the following would indicate the beginning of cytokinesisin plant cells
Antigen processing would involve which of the following for antigen -presenting cells? The immune cells take...
Antigen processing would involve which of the following for antigen -presenting cells? The immune cells take peptides 8 - 10 amino acids long directly from which organelle in the cytosol? How does the immune system recognize that a cell is infected with a virus?
Generally speaking, which of the following mutations would most severely affect the protein coded for by a gene?
Generally speaking, which of the following mutations would most severely affect the protein coded for by a gene? a base substitution at the beginning of the gene a base substitution at the end of the gene a frameshift deletion at the beginning of the gene a frameshift deletion at the end of the gene
Imagine an herbicide inhibited the proton (H+) pumps in the plasma membrane of the cells in a plant stem
  Imagine an herbicide inhibited the proton (H+) pumps in the plasma membrane of the cells in a plant stem. How would that affect the activity of the enzymes involved in cell growth? What would be the specific consequence for the cell?
Which of the following should not affect the frequency with which mutations are induced in a...
Which of the following should not affect the frequency with which mutations are induced in a gene: A. The fidelity of the replicating DNA polymerase. B. Exposure to a chemical mutagen. C. The size of the gene (in base pairs). D. The function of the encoded protein. (Please answer this question explaining why every other choices are incorrect along with defining any necessary key concepts to help determining why you choose and not choose the choice(s). Be neat with all...
You find some cells have mutations that permanently deactivate Raf. Pleasure list the protein(s) that would...
You find some cells have mutations that permanently deactivate Raf. Pleasure list the protein(s) that would be an effective drug target for reversing the effect of the Raf mutation and explain your reasoning.
Which of the following types of B-cells would be considered the “youngest” type and the "oldest"...
Which of the following types of B-cells would be considered the “youngest” type and the "oldest" type?   a. Effector B-cell b. Immature B-cell c. Naive B-cell
Which of the following types of T-cells would be considered the “youngest” type and the "oldest"...
Which of the following types of T-cells would be considered the “youngest” type and the "oldest" type? a. Effector T-cell b. Immature T-cell c. Naive T-cell
ADVERTISEMENT
ADVERTISEMENT
ADVERTISEMENT