Generally speaking, which of the following mutations would most severely affect the protein coded for by a gene?

a base substitution at the beginning of the gene
a base substitution at the end of the gene
a frameshift deletion at the beginning of the gene
a frameshift deletion at the end of the gene

Solutions

Expert Solution

deleting one base pair yields the change in the amino acid coded for every codon following the deletion. deletion at the beginning of the gene will change more codons and eventually more amino acids.

a frameshift deletion at the beginning of the gene.

Dr. OWL answered 3 years ago

Next > < Previous

Related Solutions

Assuming that the mutations are adaptive, how would that affect the stability of a protein at...

Assuming that the mutations are adaptive, how would that affect the stability of a protein at low and high temperatures? Given: 1) Glutamine to lysine in a warm adapted species.Glutamine is uncharged while lysine is positively charged, therefore there would likely be a change as an uncharged amino acid is being replaced with positively charged amino acid. 2) Threonine to Alanine in a warm adapted species. Threonine is polar uncharged while Alanine is hydrophobictherefore there would likely be a change,...

Where would you expect to find mutations that reduce the expression of a bacterial protein-coding gene?...

Where would you expect to find mutations that reduce the expression of a bacterial protein-coding gene? At least two different sites are possible

Contrast experimental with quasi-experimental methods; generally speaking, which methods are most useful?

Generally speaking, would you say that most people can be trusted? A random sample of n1...

Generally speaking, would you say that most people can be trusted? A random sample of n1 = 250 people in Chicago ages 18-25 showed that r1 = 41 said yes. Another random sample of n2 = 280 people in Chicago ages 35-45 showed that r2 = 75 said yes. Does this indicate that the population proportion of trusting people in Chicago is higher for the older group? Use α = 0.05. (a) What is the level of significance? State the...

Which of the following scenarios is an example of additivity? Mutations in the gene encoding the...

Which of the following scenarios is an example of additivity? Mutations in the gene encoding the parahydroxylase enzyme can cause both cognitive impairment and albinism. Human hair color is determined by the combined effects of multiple genes. In laborador retrievers, mutations the effect of mutations at the B locus on coat color (converts brown to black melanin depends on an individual's genotype at the E locus (deposits melanin into hair follicle) In budgie birds, the B and Y genes act...

Which of the following should not affect the frequency with which mutations are induced in a...

Which of the following should not affect the frequency with which mutations are induced in a gene: A. The fidelity of the replicating DNA polymerase. B. Exposure to a chemical mutagen. C. The size of the gene (in base pairs). D. The function of the encoded protein. (Please answer this question explaining why every other choices are incorrect along with defining any necessary key concepts to help determining why you choose and not choose the choice(s). Be neat with all...

A cell-coded protein that is formed in response to infection, with most animal viruses, is called...

A cell-coded protein that is formed in response to infection, with most animal viruses, is called (a) histone (b) antibody (c) interferon (d) antigen.

how do non protein coding sequences affect gene expression and protein activity

Most antimicrobials that arrest protein function are non-selective as to the microbes they affect. Why would...

Most antimicrobials that arrest protein function are non-selective as to the microbes they affect. Why would this be? What would the effect of these agents be on human skin or tissue, if applied there?

Which of the following approaches is most likely to identify a gene?

Which of the following approaches is most likely to identify a gene?Identifying sequences that are not different between two species.Identifying regions of that genome that are not transcribed.Identifying sequences that can be deleted without any phenotypic effect.Identifying sequences that do not have open reading frames.

Subjects